Asmalin Overdosage

Syrup: Overdosage with salbutamol produces symptoms that may be expected with beta₂-agonists such as tachycardia, central nervous system stimulation, tremor, hypokalemia, and hypoglycemia.
Nausea, vomiting and hyperglycemia have been reported, predominantly in children and when salbutamol overdose has been taken via the oral route.
Lactic acidosis has been reported in association with high therapeutic doses as well as overdoses of short-acting beta-agonist therapy.
Cardiac arrest and even death may occur following excessive use of salbutamol.
Discontinue salbutamol and institute appropriate symptomatic therapy in cases of salbutamol overdosage. Administration of a beta-adrenergic blocking agent may be appropriate, but use with caution in patients with a history of bronchospasm. There is no adequate evidence to support the use of dialysis in the treatment of salbutamol overdose.
Pulmoneb: Symptoms of nebulized Salbutamol overdose include extensions of the common undesirable effects (e.g., tremors, seizure, nervousness, dizziness, headache, sleeplessness/insomnia, hypertension or hypotension, palpitation, tachycardia, arrhythmia, angina, dry mouth, nausea, fatigue, and malaise).
Excessive use of oral sympathomimetic inhalations may result in cardiac arrest and even fatalities. Hypokalemia has also been reported. Thus, plasma potassium concentrations should be monitored. Discontinue Salbutamol and institute appropriate symptomatic therapy in cases of Salbutamol overdosage. Administration of a beta-adrenergic blocking agent may be appropriate, but use with caution if the patient is asthmatic. There is no adequate evidence to support the use of dialysis in the treatment of Salbutamol overdose.