Arasid-100/Arasid-500/Arasid-1000 Caution For Usage

Incompatibilities: Incompatibilities with: carbenicillin sodium, cephalothin sodium, gentamicin sulphate, Heparin sodium, hydrocortisone sodium succinate, insulin regular, Methotrexate, 5-fluorouracil, nafcillin sodium, oxacillin sodium, penicillin G sodium (benzyl penicillin), methyl-prednisolone sodium succinate and prednisolone succinate.
However, the incompatibility depends on several factors (e.g concentrations of the drug, specific diluents used, resulting pH, temperature). Specialised references should be consulted for specific compatibility information.
This medicinal product must not be mixed with other medicinal products excepts those mentioned in Special precautions for disposal and other handling as follows.
Special precautions for disposal and other handling: For single use only.
If solution appears discoloured or contains visible particles, it should be discarded.
Once opened, the contents of each vial must be used immediately. Discard any unused contents.
Water for injections, 0.9% w/v saline or 5% w/v dextrose are commonly used infusion fluids for Cytarabine (see Shelf life under Storage). Cytarabine injection should not to be mixed any other medicinal products except those mentioned as follows.
Cytotoxic Handling Guidelines Administration: Should be administered by, or under the direct supervision of a qualified physician who is experienced in the use of cancer chemotherapeutic agents.
Preparation: Chemotherapeutic agents should be prepared for administration only by professionals trained in the safe use of the preparation.
Operations such as dilution and transfer to syringes should be carried out only in the designated area.
The personnel carrying out these procedures should be adequately protected with clothing, gloves and eye shield.
Pregnant personnel are advised not to handle chemotherapeutic agents.
Disposal and Contamination: Any unused product or waste material should be disposed of in accordance with local requirements. To destroy, place in a high risk (for cytotoxics) waste disposal bag and incinerate at 1100°C.
Any unused product or waste material should be disposed of in accordance with local requirements.
If spills occur, restrict access to the affected area and adequate protection including gloves and safety spectacles should be worn. Limit the spread and clean the area with absorbent paper/material. Spills may also be treated with 5% sodium hypochlorite. The spill area should be cleaned with copious amounts of water. Place the contaminated material in a leak proof disposal bag for cytotoxics and incinerate at 1100°C.