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Amara: An increased hypoglycemic effect has occurred or might be expected with ACE Inhibitors, alcohol, allopurinol some analgesics (notably azapropazone, phenylbutazone and the salicylates), azoles, antifungals, (fluconazole, ketoconazole and miconazole), chloramphenicol, cimetidine, clofibrate and related compounds, coumarin anticoagulants, halofenate, heparin, MAOI's, octreotide (also this may also produce hyperglycemia), ranitidine, sulphinpyrazone, sulphonamides (including co-trimoxazole), tetracyclines, tricyclic antidepressants, and thyroid hormones.
Amara-4: With NSAID's e.g., Salicylates, Sulphonamides, Chloramphenicol, Coumadin and Probenecid may potentiate the hypoglycemic action of Glimepiride Thiazides, other diuretic, phenothiazines, thyroid products, oral contraceptives and phenytoin tend to produce hyperglycemic.
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