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History of Intracranial Hemorrhage: Ticagrelor is contraindicated in patients with a history of intracranial hemorrhage (ICH) because of a high risk of recurrent ICH in this population.
Active Bleeding: Ticagrelor is contraindicated in patients with active pathological bleeding such as peptic ulcer or intracranial hemorrhage.
Hypersensitivity: Ticagrelor is contraindicated in patients with hypersensitivity (e.g., angioedema) to Ticagrelor or any component of the product.
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