100 mg once daily as monotherapy or in combination therapy. Patient w/ moderate renal insufficiency (CrCl ≥30 to <50 mL/min) 50 mg once daily. Patient w/ severe renal insufficiency (CrCl <30 mL/min), ESRD requiring hemodialysis or peritoneal dialysis 25 mg once daily.
Discontinue use if pancreatitis occurs. Hypoglycemia. Patients w/ renal insufficiency. Not recommended during pregnancy. Do not use during lactation. Childn <18 yr.
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