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Care must be exercised in patients with very low blood pressure (severe hypotension with systolic pressure <90 mm Hg), in cases of manifest heart failure and in the case of severe aortic stenosis.
Careful monitoring of blood pressure must be exercised, also when administering nifedipine with IV magnesium sulfate, owing to the possibility of an excessive fall in blood pressure which could harm both mother and fetus.
As with other nondeformable material, care should be used when administering Adalat GITS 30 in patients with preexisting severe gastrointestinal narrowing because obstructive symptoms may occur.
Bezoars can occur in very rare cases and may require surgical intervention.
In single cases obstructive symptoms have been described without known history of gastrointestinal disorders.
When doing barium contrast x-ray, Adalat GITS may cause false positive effects (eg, filling defects interpreted as polyp).
In patients with impaired liver function, careful monitoring and, in severe cases, a dose reduction may be necessary.
Effects on the Ability to Drive or Operate Machinery: Reactions to the drug, which vary in intensity from individual to individual, can impair the ability to drive or to operate machinery. This applies particularly at the start of treatment, on changing the medication and in combination with alcohol.
