Acellbia Dosage/Direction for Use

The dose of Rituximab needed depends on the body weight and the type of cancer to be treated. The recommended dose is 5 mg, 7.5 mg, 10 mg, or 15 mg per kilogram of a patient's body weight. Treatment with Rituximab will be once every 2 or 3 weeks.
Non-Hodgkin's Lymphoma: If Rituximab is used alone, it will be given once a week for 4 weeks. Repeated treatment courses with Rituximab are possible. If Rituximab with chemotherapy, it will be given on the same day as the chemotherapy. This is usually given 3 weeks up to 8 times.
If responds well to the treatment, Rituximab as maintenance treatment may be given every 2 or 3 months for two years.
Chronic Lymphocytic Leukemia: If treated with Rituximab in combination with chemotherapy, Rituximab infusions on Day 0 cycle 1 then Day 1 of each cycle for 6 cycles in total. Each cycle has a duration of 28 days. The chemotherapy should be given after the Rituximab infusion. Physician has to decide whether patients should receive concomitant supportive therapy.
Granulomatosis with Polyangiitis (Wegener's) (GPA) and Microscopic Polyangiitis (MPA): Treatment with Rituximab uses four separate infusions given at weekly intervals.
Corticosteroids will usually be given by injection before the start of Rituximab treatment. Corticosteroids given by mouth may be started at any time by the physician to treat.