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Treatment of adult patients with metastatic carcinoma of the colon or rectum (in combination with fluoropyrimidine based chemotherapy).
First-line treatment of non-squamous non-small cell lung cancer (NSCLC) in combination with platinum-based chemotherapy.
Treatment of glioblastoma, as a single agent for adult patients with progressive disease following prior therapy.
First-line treatment (in combination with interferon alpha-2a) of adult patients with advanced and/or metastatic renal cell cancer.
Front-line treatment (in combination with carboplatin and paclitaxel) of adult patients with advanced (International Federation of Gynecology and Obstetrics [FIGO] stages III B, III C and IV) epithelial ovarian, fallopian tube, or primary peritoneal cancer.
Treatment of persistent, recurrent, or metastatic carcinoma of the cervix in adult patients, in combination with paclitaxel and cisplatin; or, alternatively, paclitaxel and topotecan (for those who cannot receive platinum therapy).
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