Zopam Injection Dosage/Direction for Use

Usual adult dose: States of excitation: 10-20 mg three times daily IM or IV until acute symptoms subside.
Status epilepticus: Initial dose 10-20 mg IV.; in the following hours 20 mg IM or by intravenous drip infusion, as necessary.
Muscular spasm: 10 mg once or twice IV.
Tetanus: 10 mg IV relieves the spastic state for about 8 hours.
Usual paediatric dose: Anticonvulsant: Status epilepticus and severe recurrent convulsive seizures: Children 2 to 5 years of age: Intravenous (slow), 200 to 500 mcg (0.2 to 0.5 mg) every two to five minutes up to a maximum of 5 mg. If necessary, therapy may be repeated in two to four hours.
Children 5 years of age and over: Intravenous (slow), 1 mg every two to five minutes up to a maximum of 10 mg. If necessary, therapy may be repeated in two to four hours.
Note: The intravenous route of administration is preferred; however, if intravenous administration is impossible, the intra-muscular route of administration may be used.
Skeletal muscle relaxant adjunct: Tetanus: Children 2 to 5 years of age: Intramuscular or intravenous, 1 to 2 mg, the dosage being repeated every three or four hours as needed.
Children 5 years of age and over: Intramuscular or intravenous, 5 to 10 mg, the dosage being repeated every three or four hours as needed.
Note: When the intravenous route is used in children, it is recommended that the medication be administered slowly over a three-minute period in a dosage not to exceed 250 mcg (0.25 mg) per kg of body weight. After an interval of fifteen to thirty minutes, the dosage may be repeated.
Usual geriatric dose: Antianxiety agent or Sedative-hypnotic or Amnestic or Anticonvulsant or Skeletal muscle relaxant adjunct: Intramuscular or intravenous, initially 2 to 5 mg per dose, the dosage being increased gradually as needed and tolerated.