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Sterile, clear, colourless to pale yellow, iso-osmotic solution, pH 6.2, preservative-free.
1 mL solution for injection contains 40 mg aflibercept*.
One vial contains an extractable volume of at least 0.1 mL, equivalent to at least 4 mg aflibercept. This provides a usable amount to deliver a single dose of 0.05 mL containing 2 mg aflibercept.
*Fusion protein consisting of portions of human VEGF (vascular endothelial growth factor) receptors 1 and 2 extracellular domains fused to the Fc portion of human IgG1 and produced in Chinese hamster ovary (CHO) K1 cells by recombinant DNA technology.
Yesafili has been developed as Biosimilar Product to Eylea.
Yesafili is available in the following pack: One pack containing 1 vial and a 5-micron sterile filter needle (18 G ×1½-inch).
Excipients/Inactive Ingredients: Histidine, Histidine hydrochloride monohydrate, Polysorbate 20, Trehalose dihydrate, Water for injections.
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