Xigatin Indications/Uses

Monotherapy: Xigatin is indicated as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.
Combination with metformin: Xigatin is indicated in patients with type 2 diabetes mellitus to improve glycemic control in combination with metformin as initial therapy or when the single agent alone, with diet and exercise, does not provide adequate glycemic control. Initial combination therapy or maintenance of combination therapy may not be appropriate for all patients. These management options are left to the discretion of the health care provider.
Combination with a sulphonylurea: Xigatin is indicated in patients with type 2 diabetes mellitus to improve glycemic control in combination with a sulphonylureas when treatment with maximal tolerated dose of sulphonylurea alone, with diet and exercise, does not provide adequate glycemic control and when metformin is inappropriate due to contraindications or intolerance.
Combination with metformin and a sulphonylurea: Xigatin is indicated in patients with type 2 diabetes mellitus to improve glycemic control in combination with metformin and a sulphonylurea when dual therapy with these two agents and with diet and exercise does not provide adequate glycemic control.
Combination with a peroxisome pro/iterator-activated receptor gamma (PPARy) agonist: Xigatin is indicated in patients with type 2 diabetes mellitus to improve glycemic control in combination with a PPARy agonist (i.e. thiazolidinediones) when diet and exercise, plus the single agent do not provide adequate glycemic control.
Combination with metformin and a PPARy agonist: Xigatin is indicated in patients with type 2 diabetes mellitus to improve glycemic control in combination with metformin and a PPARy agonist (i.e., thiazolidinediones) when dual therapy with these agents, with diet and exercise, does not provide adequate glycemic control.
Combination with Insulin: Xigatin is indicated in patients with type 2 diabetes mellitus as an adjunct to diet and exercise to improve glycemic control in combination with insulin (with or without metformin).