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Vaxcel Polymyxin E

Vaxcel Polymyxin E Overdosage

colistimethate sodium

Manufacturer:

Kotra Pharma

Distributor:

Kotra Pharma
Full Prescribing Info
Overdosage
Overdose can result in neuromuscular blockade that can lead to muscular weakness, apnoea and possible respiratory arrest. Overdose can also cause acute renal failure characterised by decreased urine output and increased serum concentrations of BUN and creatinine. There is no specific antidote, manage by supportive treatment. Measures to increase the rate of elimination of Colistimethate sodium e.g. mannitol diuresis, prolonged haemodialysis or peritoneal dialysis may be tried, but effectiveness is unknown.
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