Ufur Dosage/Direction for Use

UFUR capsules are administered orally. The usual dosage is (Tegafur: 300–600 mg) 3–6 capsules daily in 2 -3 divided doses. For patients with cervical cancer, the usual dosage in 6 capsules (Tegafur 600 mg) daily in 2-3 divided doses. Even in combination chemotherapy with other antineoplastics, the drug is given as described previously. (See Table 2.)

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Folinate plus Tegafur-Uracil combination therapy: For colorectal cancer, Tegafur-Uracil is to be administered at a typical daily dose equivalent to 300-600 mg tegafur (the standard rate: equiv. 300 mg tegafur/m²) orally in three divided doses (at an interval of approx. 8 hours) more than 1 hour before or after meal. A typical daily dose of Folinate is 75 mg for adults, administered orally in three divided doses (at an interval of approx. 8 hours) together with Tegafur-Uracil. Repeat a course of a consecutive 28-day administration period followed by a 7-day rest period.
Precautions on Dosage and Administration: Folinate plus Tegafur-Uracil combination therapy: Meals affect the efficacy of Folinate plus Tegafur-Uracil combination therapy. Administration should be withheld during one hour before or after meal.
See the standard administration schedule shown as follows. (See Table 3.)

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