Tiaprofenic acid - Oral

Tiaprofenic acid helps relieve pain and inflammation associated with joint disorders such as ankylosing spondylitis (inflammation in joints of the spine), rheumatoid arthritis (inflammation in joints of fingers, wrist, feet, ankles), and osteoarthritis (joint pain and stiffness due to damage in joint surfaces).

This medicine may also be used to relieve pain and inflammation associated with sprains, strains, and lower back pain.

Tiaprofenic acid may be used to treat other conditions as decided by your doctor.

Take Tiaprofenic acid exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Take it together with food or immediately after a meal.

Swallow the tablet whole with a glass of water.

You may stop taking this medicine when you have no more swelling or pain.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

Do not take this medicine if you ever had an allergic reaction (e.g. rashes, breathlessness, swollen eyes) to Tiaprofenic acid or other similar medicines such as aspirin, ibuprofen or other NSAIDs (medicines for pain and inflammation).

Alert your doctor if you have the following conditions:

• active or a history of recurrent stomach ulcer or bleeding
• active inflammatory disease of the stomach or bowel
• history of bleeding or hole in the stomach or bowel caused by taking NSAIDs
• bladder or prostate problems e.g. pain or blood in urine, frequent urge to urinate
• history of recurrent problems in passing urine
• existing or history of asthma
• severe heart disease
• severe kidney disease
• severe liver disease

as this medicine may not be suitable for you.

Do not take Tiaprofenic acid if you are in your 3rd trimester of pregnancy. This medicine may cause harm to your unborn child.

Do not take this medicine with other NSAIDs, such as ibuprofen, celecoxib, diclofenac, and aspirin.

Inform your doctor if you have the following conditions:

• history of stomach disease e.g. ulcerative colitis (inflammation of the large intestines), Crohn’s disease (long-standing inflammatory disease of the digestive tract)
• if you often have rhinosinusitis (inflammation of the inside lining of the nose resulting in nasal congestion)
• hives or red, itchy bumps
• noncancerous growths in the lining of the nose
• blood clotting problems
• bleeding in the brain
• heart disease e.g. mild to moderate heart failure
• cerebrovascular disease (a disorder of the blood vessels to the brain)
• high blood pressure
• high cholesterol levels in the blood
• diabetes
• systemic lupus erythematosus or lupus (an autoimmune disease that causes inflammation)
• liver disease
• kidney disease

Let your doctor know if you are breastfeeding, planning to get pregnant, or in your 1st or 2nd trimester of pregnancy.

Be sure to check with your doctor or pharmacist before giving Tiaprofenic acid to the elderly. Elderly people may be more sensitive to the side effects.

Inform your doctor if you are an active smoker.

If you are going to have an operation, including minor surgery and dental work, inform your doctor or dentist that you are taking this medicine.

Avoid long-term use of any painkillers.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.

• Routine tests (e.g. liver or kidney function, electrolyte levels, complete blood count, eye examination) may be done while you are being treated with this medicine. Your doctor will advise you about how often you need to have these tests.
• Regular monitoring of your weight and signs and symptoms of side effects (e.g. stomach pain or bleeding, unusual bruising) may also be needed.

Tiaprofenic acid may cause drowsiness, dizziness or blurred vision. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.

Other side effects include any of the following: nausea, vomiting, diarrhoea, indigestion, headache, constipation, itching, and ringing in the ears.

This medicine may also make your skin more sensitive to sunlight. Apply sunscreen when going outdoors and avoid prolonged exposure to sunlight and UV lamps.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:

• rashes, breathlessness, swelling of the face, eyes or mouth
• pass out bloody or black as tar stools and vomiting blood or ground coffee-like material
• rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
• yellowing of the skin or eyes, abdominal pain, dark coloured urine, tiredness, swelling in the legs and ankles
• pain in the bladder or when urinating
• unable to pass urine, blood in urine
• unusual bleeding or bruising, frequent and persistent sore throat with fever
• muscle weakness, cramping or numbness; fast or irregular heartbeat
• difficulty breathing, wheezing, tightness in the chest
• change in balance, weakness on one side of the body, trouble speaking or thinking

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.

Do not take Tiaprofenic acid with other NSAIDs (medicines for pain and inflammation) e.g. ibuprofen, celecoxib, diclofenac and aspirin.

Inform your doctor and pharmacist if you are taking or using any of these medicines:

• certain medicines for diabetes
• anti-inflammatory medicines e.g. prednisolone
• blood-thinning medicines e.g. heparin, warfarin, clopidogrel, dabigatran
• medicines to treat depression e.g. sertraline, citalopram, fluoxetine
• medicines for high blood pressure e.g. amlodipine, losartan
• medicines for HIV infection e.g. tenofovir disoproxil fumarate, zidovudine
• medicines used in organ transplant or certain immune disorders e.g. tacrolimus, ciclosporin
• water pills or medicines for water retention e.g. spironolactone
• digoxin (medicine for heart disease)
• nicorandil (medicine for chest pain)
• pentoxifylline (medicine used to improve blood flow to arms and legs)
• certain antibiotics e.g. amikacin, ciprofloxacin
• methotrexate (medicine for cancer)
• lithium (medicine for mood disorder)
• probenecid (medicine for gout or high uric acid level in the blood)

This list does not include all medicines that may interact with Tiaprofenic acid.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.

Avoid alcohol.

Store in a cool, dry place away from the reach of children.

Protect from light and high humidity.

Medicines must not be used past the expiry date.