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Toxicity from dihydrocodeine is typical of opiates and includes pinpoint pupils, respiratory depression, and loss of consciousness. Convulsions, cardiovascular collapse and death may occur.
Conservative management is recommended; gastric lavage should be carried out. Severe respiratory depression can be treated with naloxone HCl 0.4-2 mg subcutaneously, repeated as required at 2 or 3 min intervals.
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