Renson Dosage/Direction for Use

Recommended dose: Posology: As replacement therapy, 20 to 30 mg daily, usually approximately ²/₃ of this amount in the morning and ¹/₃ in the early evening. If necessary, the morning dose may be taken in 2 parts. In the other indications, 40 to 200 mg daily; in short-term use in special indications, even higher doses.
Paediatric population: In children, the dosage is individual. In adrenocortical insufficiency, 7.5 to 15 mg/m²/day divided in 3 equal doses (first thing in the morning, in the afternoon, and late in the evening); the morning dose may also be larger than the other doses. In congenital adrenal hyperplasia, usually 10 mg/m²/day divided in 3 doses. In hypopituitarism, 2.5 mg 3 times daily.
Dosing in special situations: Hydrocortisone replacement therapy: In patients receiving hydrocortisone replacement therapy, the dosage of Hydrocortisone should be increased 2-4-fold in stressful situations, such as in connection with injuries, infections or surgery. If necessary, the patient should be switched to parenteral treatment.
Pharmacological glucocorticoid therapy: Long-term systemic glucocorticoid therapy causes adrenocortical insufficiency that may persist for months after treatment cessation. Therefore, the dosage of Hydrocortisone should be increased in stressful situations such as in connection with infections.
In order to avoid glucocorticoid withdrawal syndrome, long-term treatment with corticosteroids should be discontinued gradually over several weeks. Dosing on alternate days reduces the risk of adrenocortical insufficiency and of the withdrawal syndrome associated with treatment cessation.
Instructions for Use: The patient should take this medicine by mouth. The amount to take each day will depend on the illness. The number of tablets to be taken will be on the label of the medicine. If unsure about the dose to take, talk to a doctor or pharmacist. Hydrocortisone can be taken with or without food.
Mode of Administration: Oral.