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Clear to slightly opalescent, colourless to slightly brownish-yellow aqueous solution.
One ml solution for injection contains 120 mg of brolucizumab*.
* Brolucizumab is a humanised monoclonal single-chain Fv (scFv) antibody fragment produced in Escherichia coli cells by recombinant DNA technology.
Pagenax 120 mg/ml solution for injection: Each vial contains 27.6 mg brolucizumab in 0.23 ml solution. This provides a usable amount to deliver a single dose of 0.05 ml solution containing 6 mg of brolucizumab.
Excipient with known effect: Each vial contains 0.05 mg polysorbate 80 in 0.23 ml solution. This corresponds to 0.01 mg polysorbate 80 per dose (0.05 ml).
Excipients/Inactive Ingredients: Sodium citrate, Sucrose, Polysorbate 80, Water for injections.
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