Oxiconazole: Uses, Dosage, Side Effects and More

Generic Medicine Info Patient Medicine Information

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Indications and Dosage

Topical/Cutaneous
Tinea corporis, Tinea cruris, Tinea pedis

Adult: As 1% cream or lotion: Apply to the affected and immediately surrounding area(s) once daily to bid. Treatment duration: 2 weeks (tinea corporis and tinea cruris); 1 month (tinea pedis).

Topical/Cutaneous
Tinea versicolor

Adult: As 1% cream: Apply to the affected and immediately surrounding area(s) once daily for 2 weeks.

Contraindications

Hypersensitivity.

Special Precautions

Pregnancy and lactation.

Adverse Reactions

Significant: Sensitivity or irritation.
Skin and subcutaneous tissue disorders: Pruritus, localised burning, allergic contact dermatitis, folliculitis, rash, papule, nodules, erythema, skin fissure, dyshidrotic eczema, maceration, stinging, scaling, or tingling of the skin.

Patient Counseling Information

Avoid contact with eyes, nose, mouth, vagina, or other mucous membranes.

Monitoring Parameters

Monitor for signs of increased skin irritation or sensitivity.

Action

Description:
Mechanism of Action: Oxiconazole is an imidazole antifungal that inhibits the biosynthesis of ergosterol, a critical component of fungal cellular membrane integrity.
Pharmacokinetics:
Absorption: Low systemic absorption.
Distribution: Enters breast milk.
Excretion: Via urine (<0.3%).

Chemical Structure

Storage

Store between 15-30°C.

MIMS Class

Topical Antifungals & Antiparasites

ATC Classification

D01AC11 - oxiconazole ; Belongs to the class of imidazole and triazole derivatives. Used in the topical treatment of fungal infection.

References

Anon. Oxiconazole. AHFS Clinical Drug Information [online]. Bethesda, MD. American Society of Health-System Pharmacists, Inc. https://www.ahfscdi.com. Accessed 08/07/2024.

Brayfield A, Cadart C (eds). Oxiconazole Nitrate. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 05/07/2024.

Oxiconazole Nitrate Cream (E. Fougera & Co., A Division of Fougera Pharmaceuticals Inc.). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed. Accessed 05/07/2024.

Oxiconazole. Gold Standard Drug Database in ClinicalKey [online]. Elsevier Inc. https://www.clinicalkey.com. Accessed 08/07/2024.

Oxiconazole. UpToDate Lexidrug, Lexi-Drugs Multinational Online. Waltham, MA. UpToDate, Inc. https://online.lexi.com. Accessed 05/07/2024.

Oxistat Lotion (ANI Pharmaceuticals, Inc.). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed. Accessed 05/07/2024.

Disclaimer: This information is independently developed by MIMS based on Oxiconazole from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2025 MIMS. All rights reserved. Powered by MIMS.com