Nedocromil: Uses, Dosage, Side Effects and More

Generic Medicine Info Patient Medicine Information

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Indications and Dosage

Ophthalmic
Allergic conjunctivitis

Adult: As 2% solution or drops: Instil 1-2 drops in each eye bid. Continue treatment throughout the period of exposure to allergen.

Special Precautions

Pregnancy and lactation.

Adverse Reactions

Eye disorders: Eye irritation, stinging of eyes, burning sensation of eye, eye redness, photophobia, conjunctivitis.
Gastrointestinal disorders: Unpleasant taste.
Nervous system disorders: Headache.
Respiratory, thoracic and mediastinal disorders: Nasal congestion, rhinitis, asthma.

Pregnancy Category (US FDA)

Inhalation/Respiratory/Ophth: B

Patient Counseling Information

Avoid wearing contact lenses during therapy.

Action

Description:
Mechanism of Action: Nedocromil, a mast cell stabiliser, inhibits the release of mediators from cells associated with hypersensitivity reactions such as eosinophils, neutrophils, macrophages, mast cells, monocytes and platelets. Additionally, it blocks the release of histamine, leukotrienes, and the slow-reacting substance of anaphylaxis.
Pharmacokinetics:
Excretion: Via urine 70% (as unchanged drug); faeces 30% (as unchanged drug).

Chemical Structure

Storage

Store between 2-25°C.

MIMS Class

Ophthalmic Decongestants, Anesthetics, Anti-Inflammatories

ATC Classification

S01GX04 - nedocromil ; Belongs to the class of other ophthalmologic antiallergics.

References

Alocril (Allergan, Inc.). U.S. FDA. https://www.fda.gov. Accessed 04/09/2024.

Alocril Solution/Drops (Allergan, Inc.). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed. Accessed 04/09/2024.

Brayfield A, Cadart C (eds). Nedocromil Sodium. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 04/09/2024.

Nedocromil. Gold Standard Drug Database in ClinicalKey [online]. Elsevier Inc. https://www.clinicalkey.com. Accessed 04/09/2024.

Nedocromil. UpToDate Lexidrug, Lexi-Drugs Multinational Online. Waltham, MA. UpToDate, Inc. https://online.lexi.com. Accessed 04/09/2024.

Disclaimer: This information is independently developed by MIMS based on Nedocromil from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2025 MIMS. All rights reserved. Powered by MIMS.com