Levores Dosage/Direction for Use

Recommended Dosage: Levores 5mg/ml Solution for Infusion should only be administered by IV infusion. It is not for IM, intrathecal, intraperitoneal or SC administration.
Caution: Rapid or bolus IV infusion must be avoided. Levofloxacin injection should be infused IV slowly over a period of not less than 60 or 90 min, depending on the dosage (see Precautions).
Usual Dose: 250 or 500 mg administered by slow infusion over 60 min every 24 hours or 750 mg administered orally or by slow infusion over 90 min every 24 hours, as indicated by infection and described in the following dosing chart. These recommendations apply to patients with normal renal function (ie, creatinine clearance >80 mL/min). For patients with altered renal function, see Table 2.
Patients with Normal Renal Function: See Table 1.

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Patients with Impaired Renal Function: See Table 2.

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When only the serum creatinine is known, the following formula may be used to estimate creatinine clearance: See equation.

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The serum creatinine should represent a steady state of renal function.
Mode of Administration: Intravenous Infusion.