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One ml of concentrate contains 40 mg cabazitaxel.
Each vial of 1.5 ml (nominal volume) of concentrate contains 60 mg cabazitaxel.
After initial dilution with the entire solvent, each ml of solution contains 10 mg cabazitaxel.
Note: Both the JEVTANA 60 mg/1.5 ml concentrate vial (fill volume: 73.2 mg of cabazitaxel/1.83 ml) and the solvent vial (fill volume: 5.67 ml) contain an overfill to compensate for liquid loss during preparation. This overfill ensures that after dilution with the ENTIRE contents of the accompanying solvent, there is solution containing 10 mg/ml cabazitaxel.
Excipients with known effect: Each vial of solvent contains 573.3 mg of ethanol 96%.
Excipients/Inactive Ingredients: Concentrate: Polysorbate 80, Citric acid.
Solvent: Ethanol 96%, Water for injections.
