Prevention of resp distress syndrome (RDS) in premature infants at high risk for RDS & treatment ("rescue") of premature infants who develop RDS. Decreases the incidence of RDS, mortality due to RDS & air leaks associated w/ RDS. Prophylaxis therapy at birth for premature infants <29 wk of gestational age at significant risk for RDS. Treatment therapy for infants ≤72 hr of age w/ RDS (confirmed by clinical & radiologic findings) & requiring endotracheal intubation.
Not a substitute for neonatal intensive care. Monitor resp status regularly. Transient episodes of reflux into the endotracheal tube, cyanosis, bradycardia or airway obstruction. Patients w/ both intraventricular hemorrhage (IVH) & periventricular leukomalacia (PVL).
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