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The solution is clear to slightly opalescent and colourless to slightly yellow. The solution pH is in the range of 5.7-6.3 and the osmolality is between 258 and 311 mOsm/kg.
Each pre-filled syringe contains 100 mg of tildrakizumab in 1 mL.
Tildrakizumab is a humanised IgG1/k monoclonal antibody produced in Chinese Hamster Ovary (CHO) cells by recombinant DNA technology.
Excipient with known effect: Each Tildrakizumab 100 mg solution for injection in pre-filled syringe contains 0.5 mg of polysorbate 80 (E 433).
Excipients/Inactive Ingredients: L-Histidine, L-Histidine hydrochloride monohydrate, Polysorbate 80 (E 433), Sucrose, Water for injections.
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