Glumet DC Drug Interactions

Acute alcohol intoxication may increase the risk of lactic acidosis, particularly in case of fasting or malnutrition and hepatic insufficiency. To avoid consumption of alcohol and alcohol-containing medications.
Intravascular administration of iodinated contrast materials may lead to renal failure, resulting in metformin accumulation and a risk of lactic acidosis. Metformin should be discontinued prior to, or at the time of the test and not reinstituted until 48 hours afterwards, and only after renal function has been re-evaluated and found to be normal.
Glucocorticoids (systemic and local routes), beta-2-agonists, and diuretics have intrinsic hyperglycaemic activity. If necessary, the dosage of the antidiabetic drug need to be adjusted during therapy with the other drug and upon its discontinuation.
ACE-inhibitors may decrease the blood glucose level. If necessary, the dosage of the antidiabetic drug need to be adjusted during therapy with the other drug and upon its discontinuation.