Glice Adverse Reactions

Undesirable effects frequencies are defined as very common (≥1/10), common (≥1/100; <1/10), uncommon (≥1/1,000; <1/100), rare (≥1/10,000; <1/1,000) or very rare (<1/10,000), not known (cannot be estimated).
During administration of glyceryl trinitrate, the following undesirable effects may be observed. (See table.)

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Severe hypotensive responses have been reported for organic nitrates and include nausea, vomiting, restlessness, pallor, and excessive perspiration.
During treatment with glyceryl trinitrate, a temporary hypoxemia may occur due to a relative redistribution of the blood flow in hypoventilated alveolar areas. Particularly in patients with coronary artery disease this may lead to a myocardial hypoxia.
Like other nitrate preparations, glyceryl trinitrate commonly causes dose-dependent headaches due to cerebral vasodilation. These often regress after a few days despite the maintenance of therapy. If headaches persist during intermittent therapy, they should be treated with mild analgesics. Unresponsive headaches are an indication for reducing the dosage of glyceryl trinitrate or discontinuing treatment.
A slight reflex-induced increase in heart in heart rate can be avoided by resorting, if necessary, to combined treatment with a beta-blocker.
Reporting of suspected adverse reactions: Reporting suspected adverse reactions after authorization of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions.