Pregnancy: There are no adequate data in pregnant women. FOSEMRED should be used during pregnancy only if the potential benefit justifies the potential risk to the mother and the fetus.
Breast-feeding: FOSEMRED when administered intravenously, is rapidly converted to aprepitant.
Aprepitant is excreted in the milk of lactating rats. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the possible adverse effects of aprepitant on nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.