For oral administration to adults only.
Depression, with or without Associated Anxiety Symptoms: Adults and the Elderly: Recommended Dose: 20 mg/day.
Obsessive-Compulsive Disorder: Adults and the Elderly: 20-60 mg/day. Recommended Initial Dose: 20 mg/day. Although there may be an increased potential for side effects at higher doses, a dose increase may be considered after several weeks if there is no response.
Premenstrual Dysphoric Disorder (PMDD): Recommended Dose: 20 mg/day. Initial treatment should be limited to 6 months, after which patients should be re-assessed regarding the benefit of continued therapy.
All Indications: The recommended dose may be increased or decreased. Doses >80 mg/day have not been systematically evaluated.
Fluoxetine may be administered with or without food. When dosing is stopped, active drug substances will persist in the body for weeks. This should be borne in mind when starting or stopping treatment. Dosage tapering is unnecessary in most patients.
A lower or less frequent dose should be considered in patients with hepatic impairment, concurrent diseases, or who are taking multiple medications.
Use in children is not recommended as safety and efficacy have not been established.
Mode of Administration: Oral.