Elonza-100 Dosage/Direction for Use

Oral.
Use in adults: The recommended dose is 50 mg taken as needed approximately one hour before sexual activity. Based on efficacy and toleration, the dose may be increased to 100 mg or decreased to 25 mg. The maximum recommended dosing frequency is once per day. If Elonza is taken with food, the onset of activity may be delayed compared to the fasted state.
Use in the elderly: Dosage adjustments are not required in elderly patients.
Use in patients with impaired renal function: The dosing recommendations described in "Use in adults" apply to patients with mild to moderate renal impairment (creatinine clearance = 30-80 mL/min).
Since Sildenafil clearance is reduced in patients with severe renal impairment (creatinine clearance < 30 mL/ Min) a 25 mg dose should be considered.
Use in patients with impaired hepatic function: Since Sildenafil clearance is reduces in patients with hepatic impairment (e.g. cirrhosis) a 25 mg dose should be considered.
Use in children: Elonza is not indicated for individuals below 18 years of age. There is no relevant indication for use in children.
Use in patients using other medicines: Given the extent of the interaction with patients receiving concomitant therapy with Ritonavir, it is recommended not to exceed a maximum single dose of 25 mg of Sildenafil in a 48-hour period. A starting dose of 25 mg should be considered in patients receiving concomitant treatment with CYP3A4 inhibitors (e.g. Erythromycin, Saquimavir, Ketoconazole, Itraconazole).