Duowell Contraindications

Do not use this drug to the following patients: Patients with hypersensitivity to this product or ingredients.
During pregnancy and lactation and in women of childbearing potential not using appropriate contraceptive measures.
Telmisartan should be used during pregnancy only with caution that this drug can increase risk of spontaneous abortion and cause serious (possibly fatal) harm to an unborn baby.
Patients with cholestasis, biliary obstructive disorders or severe hepatic impairment. (Telmisartan is mostly eliminated with the bile. These patients can be expected to have reduced hepatic clearance for telmisartan.)
Patients with active liver disease including unexplained, persistent elevations of serum transaminases and any serum transaminase elevation exceeding 3 times the upper limit of normal (ULN).
Patients with myopathy.
Patients with hereditary angioedema or with a history of angioedema from ACE inhibitor or angiotensin II receptor antagonists.
Patients with severe renal impairment (creatinine clearance <30 ml/min).
Patients who take telmisartan and cyclosporine together.
The concomitant use of telmisartan and aliskiren-containing product in patients with diabetes mellitus or renal impairment (GFR<60mL/min/1.73 m²).
The 40 mg dose of rosuvastatin is contraindicated in patients with pre-disposing factors for myopathy/rhabdomyolysis. Such factors included: moderate renal impairment (creatinine clearance <60 mL/min); hypothyroidism; personal or family history of hereditary muscular disorders; previous history of muscular toxicity with another HMG-CoA reductase inhibitor or fibrate; alcohol abuse; situations where an increase in plasma levels may occur; Asian patients; concomitant use of fibrates.
This product contains lactose, so patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.