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Patients with severe liver impairment should be administered a lower initial dose because they may have reduced clearance of loratadine; an initial dose of 5 mg once daily, or 10 mg every other day is recommended.
Use in pregnancy & lactation: Safe use of Clarityne Tablet during pregnancy has not been established; therefore, use only if the potential benefit justifies the potential risk to the fetus.
Since loratadine is excreted in breast milk and because of the increased risk of antihistamines for infants, particularly newborns and premature infants, a decision should be made whether to discontinue nursing or discontinue the drug.
Use in children: Safety and efficacy of Clarityne Tablet in children <2 years have not yet been established.
