Clarithromycin Stella Adverse Reactions

After oral administration of clarithromycin, some cases of gastrointestinal disturbances (nausea, heartburns, abdominal pain, diarrhea), headache and skin rashes have been reported.
Using macrolides, transient increases of SGOT-SGPT are possible, normally reversible after therapy withdrawal. While during clinical studies with clarithromycin, more severe problems relevant to the liver have not been experienced, it should be taken into account that with antibiotics of this family, episodes of cholestatic hepatitis can exceptionally happen.
Like with other antibiotics, during therapy with clarithromycin superinfections by resistant bacteria of fungi can rarely arise, needing administration withdrawal and adoption of suitable therapies.
Skin and subcutaneous tissue disorders: Not known: Severe cutaneous adverse reactions (SCARs) including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), drug reaction with eosinophilia and systemic symptoms (DRESS) and acute generalised exanthematous pustulosis (AGEP).