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Fertility: No human studies of the effects of clotrimazole on fertility have been performed, however, animal studies have not demonstrated any effects of the drug on fertility.
Pregnancy: While there is a limited amount of clinical data in pregnant women, animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity. Clotrimazole can be used during pregnancy, but only under the direction of a Health Care Professional. During pregnancy, the treatment should be carried out with clotrimazole vaginal tablets, since these can be inserted without using an applicator.
Lactation: There are no data on the excretion of clotrimazole into human milk. However, systemic absorption is minimal after administration and is unlikely to lead to systemic effects. Clotrimazole may be used during lactation.
