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The tablet is taken orally and may be taken without regard to meal time.
Adults and children over 12 years of age: 10 mg once daily (one tablet once daily).
Children 2 to 12 years of age are dosed by weight: Bodyweight more than 30 kg: 10 mg once daily (one tablet once daily).
Bodyweight less than 30 kg: 5 mg once daily (half tablet once daily).
Efficacy and safety of Avotyne 10 mg Tablet in children under 2 years of age has not been established.
Patients with severe liver impairment should be administered a lower initial dose because they have reduced clearance of loratadine.
An initial dose of 10 mg every other day is recommended for adults and children weighing more than 30 kg, and for children weighing 30 kg or less, 5 mg every other day is recommended.
No dosage adjustments are required in the elderly or in patients with renal insufficiency.
