No clinically relevant changes in desloratadine plasma concentrations were observed in multiple-dose, ketoconazole, erythromycin, azithromycin, fluoxetine and cimetidine interaction.
There was no effect of food or grapefruit juice on the disposition of desloratadine.
Avenez Syrup taken concomitantly with alcohol did not potentiate the performance impairing effects of alcohol.