Decreased absorption with bile acid sequestrants (e.g. colestyramine); administer ezetimibe at least 2 hours before or 4 hours after the bile acid sequestrant. Increased plasma concentration with ciclosporin and gemfibrozil. Increased risk of cholelithiasis and gallbladder disease with fenofibrate. May result in increased international normalized ratio with oral anticoagulants (e.g. warfarin, fluindione).