Pregnancy: Due to the mechanism of action of angiotensin II antagonists, the risks that occur in the fetus cannot be avoided. Utero exposed to ACE inhibitors during the second and third trimesters of pregnancy has been reported to cause injury and death in developing fetuses. Besides, in retrospective data, the use of ACE inhibitors in the first trimester carries a risk of birth defects. Some reports cause the use of valsartan during pregnancy can cause spontaneous abortion, oligohydramnios and kidney disorders at birth. As a drug that works directly on RAAS, Valsartan is not recommended to be given during pregnancy (see Contraindications) or women planning for pregnancy. Professional health professionals who prescribe the RAAS group should provide counseling to pregnant women regarding the possible risks when taking this drug during pregnancy. When signs of pregnancy appear during the use of therapy, the use of valsartan is stopped immediately.
Breastfeeding: It is not known whether valsartan will be excreted in breast milk. Valsartan is excreted in breast milk in nursing mice. Thus the use of valsartan is not recommended for nursing mothers.
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