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Tramofal Plus must be used with caution and dosage reduction in patients receiving CNS. Depressants such as alcohol, opioids, anesthetic agents, narcotics, Phenothiazine, tranquilizers or sedative hypnotics. Tramadol increases respiratory and CNS risk in these patients.
Co-administration with MAO Inhibitors and Serotonin Reuptake Inhibitors.
Tramofal Plus cannot be used in conjunction with alcohol consumption.
Concomitant use with other products containing Paracetamol, because of the hepatotoxic potential of Paracetamol at high doses than the recommended dosage, then Tramofal Plus may not be used in conjunction with other products containing Paracetamol.
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