Sirinol Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Allopurinol

Indications/Uses

Reduce uric acid formation where uric acid deposits have already formed (eg, gout arthritis, skin tophi, nephrolithiasis) or other predicted clinical risks.

Dosage/Direction for Use

Adult 100 mg daily to reduce the risk of AR. Increase dose if serum uric acid response is unsatisfactory. Moderate condition 100-200 mg daily. Severe condition 300-600 mg daily. Antineoplastic-induced hyperuricemia 600-800 mg daily in 2-3 divided doses. Childn <15 yr 100-300 mg daily, monitor response for 48 hr if dose adjustment is to be made.

Administration

Should be taken with food.

Contraindications

Hypersensitivity.

Special Precautions

Discontinue immediately if itching & other hypersensitivity reactions occur. Do not start medication until acute gout attack has completely subsided. Maintain adequate hydration to avoid xanthine precipitation. Impaction of kidney stones due to uric acid.

Adverse Reactions

Rash, itching.

View ADR Reporting Link

Drug Interactions

Concomitant use w/ 6-mercaptopurine, azathioprine, vidarabine, salicylate & other uricosuric agents, chlorpropamide, coumarin anticoagulants, phenytoin, theophylline, ampicillin/amoxicillin, cyclophosphamide, doxorubicin, bleomycin, procarbazine, mechlorethamine, cyclosporin, didanosine, diuretics, ACE inhibitor.

MIMS Class

Hyperuricemia & Gout Preparations

ATC Classification

M04AA01 - allopurinol ; Belongs to the class of preparations inhibiting uric acid production. Used in the treatment of gout.

Regulatory Classification

Presentation/Packing

Form

Sirinol tab 300 mg

Packing/Price

6 × 10's

Sirinol

allopurinol

Manufacturer:

Konimex