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Experience with the use of Simulect with immunosuppressive agents other than ciclosporin for microemulsion and corticosteroids is limited. Control studies using azathioprine or mycophenolate mofetil as part of triple immunosuppressive regimen have not been performed.
Medications for the treatment of severe sensitivity reactions should be available for immediate use following administration of proteins.
Patients on immunosuppressive therapy following transplantation are at risk of developing lymphoproliferative disorders (LPDs) and opportunistic infections have been observed in patients treated with Simulect.
Effects on the Ability to Drive or Operate Machinery: Simulect is not expected to affect the ability to drive or use machines.
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