Sanofetil Mechanism of Action

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Full Prescribing Info

Action

PHARMACOLOGY: Mycophenolate mofetil is the 2-morpholinoethyl ester of mycophenolic acid (MPA). MPA is a potent, selective, uncompetitive and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH), and therefore inhibits the de novo pathway of guanosine nucleotide synthesis without incorporation into DNA. MPA has more potent cytostatic effect on lymphocytes than on other cells. SANOFETIL is effective in the prophylaxis of organ rejection in patients receiving allogeneic renal transplants and in the prophylaxis of organ rejection in patients receiving allogeneic cardiac transplants.

Sanofetil Mechanism of Action

mycophenolic acid

Manufacturer:

Sanbe