Pergoveris Caution For Usage

Instructions for Use and Handling: For single-use only.
Pergoveris must be reconstituted with the solvent before use.
The reconstituted solution should not be administered if it contains particles or is not clear. Pergoveris may be mixed with follitropin α and co-administration as a single injection.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
If Pergoveris is for self-administration, please carefully read the following instructions: Wash hands. It is important that hands and the items to be used is clean as possible.
Assemble and lay out on a clean surface all things needed: 1 vial containing Pergoveris powder, 1 solvent vial, 2 alcohol swabs, 1 syringe, 1 needle for reconstitution and a fine bore needle for SC injection, sharp container.
Remove the protective cap from the solvent vial. Attach the reconstitution needle to the syringe and draw up some air into the syringe by pulling the plunger to approximately the 1 mL mark. Then, insert the needle into the vial, push the plunger to expel the air, turn the vial upside down and gently draw up all the solvent. Set the syringe down carefully on the work-surface taking care not to touch the needle.
Prepare the Injection Solution: Remove the protective cap from the Pergoveris powder vial, pick up syringe and slowly inject the solvent into the vial of powder. Swirl gently without removing the syringe. Do not shake. After the powder has dissolved (which usually occurs immediately), check that the resulting solution is clear and does not contain any particles. Turn the vial upside down, gently draw the solution back into the syringe.
Change the needle for the fine bore needle and remove any air bubbles: If you see air bubbles in the syringe, hold the syringe with the needle pointing upwards and gently flick the syringe until all the air collects at the top. Push the plunger until the air bubbles are gone.
Immediately Inject the Solution: Wipe the chosen area with an alcohol swab. Firmly pinch the skin together and insert the needle at a 45°-90° angle using a dart-like motion. Inject under the skin, as advised by the doctor or nurse (eg, tummy, front of thigh). Do not inject directly into a vein. Inject the solution by pushing gently on the plunger. Take as much time as you need to inject all the solution. Immediately withdraw the needle and clean the skin with an alcohol swab using a circular motion.
Dispose of all used items: Once finished from injection, immediately discard all needles and empty glass containers in the sharp container provided. Any unused solution must be discarded.