Nomika Special Precautions

The use of drugs Tetracyclines during tooth growth (in the last half of pregnancy, infant, children under 8 years) may cause permanent tooth staining (yellow-grey). These side effects are more common during the use of drugs, but also repeated observations in the case of short-term treatment.
The existence of Enamel hypoplasia has also been reported, in kidney failure, usually either oral or parenteral doses.
Excessive growth can occur from the non-susceptible organisms, including fungi. If super infection occurs, discontinue treatment.
In the long-term therapy, periodic laboratory evaluation should be organ systems, including hematopoetic, kidneys and liver.
Other Effects: Tetracycline is reported to use an emergency, for anabolitic activities who was instrumental in increasing the concentration of urea in the blood.
Tetracycline also reduced plasma prothrombin activity by inhibiting the production of Vitamin K intestinal flora.
Interference with clinical pathology tests: Tetracycline can produce fluorescence in interferense Hungarty method to measure cerinary catecholamines, also reducing bacteria urobilinogen modifier bilirubin into the intestine.
High risk group: Pregnant women: Cause tooth staining in fetus.
Change the color of the teeth have been reported, but rarely in adults.
Breast milk: Tetracycline is not given as antibiotics through breast milk in children.
Neonates: Drug contraindicated because staining of teeth, enamel hypoplasia and suppress the growth of bone.
Children: Minocycline contraindicated for children under 12 years, with the same reasons as in neonates. For children over 12 years. 50 mg of Minocycline every 12 hours is recommended.
Elderly: Minocycline may be used at the normal recommended dosage in the elderly, even with mild to moderate renal impairment.