Nokoba Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Naloxone HCl

Indications/Uses

Complete or partial reversal of opioid depression & acute opioid overdosage, including resp depression, induced by natural & synthetic opioids, including propoxyphene, methadone & certain mixed agonist-antagonist analgesics: nalbuphine, pentazocine & butorphanol.

Dosage/Direction for Use

Adult Known or suspected opioid overdose 0.4-2 mg IV, may be repeated at 2-3 min intervals. If there is no response after administration of 10 mg, diagnosis of narcotic induced toxicity should be questioned. May administer by IM or SC if IV route is not available.

Special Precautions

Persons including newborns of mothers who are known or suspected to be physically dependent on opioids; abrupt & complete reversal of opioid effects may precipitate an acute w/drawal syndrome. Avoid abrupt post-op reversal of opioid depression.

Adverse Reactions

Hypotension, HTN, ventricular tachycardia & fibrillation, dyspnea, pulmonary edema, cardiac arrest, death, coma & encephalopathy w/ post-op use.

View ADR Reporting Link

Drug Interactions

Incompatible w/ bisulfite, metabisulfite, long chain or high molecular wt anions, or any soln w/ alkaline pH.

MIMS Class

Drugs Used in Substance Dependence

ATC Classification

V03AB15 - naloxone ; Belongs to the class of antidotes. Used in the management of opioid analgesic overdose.

Regulatory Classification

Presentation/Packing

Form

Nokoba inj 0.4 mg/mL

Packing/Price

2 mL x 5 × 1's (Rp350,000/boks)

Nokoba

naloxone

Manufacturer:

Fahrenheit