Lapixime Dosage & Drug Information

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Concise Prescribing Info

Contents

Cefotaxime

Indications/Uses

Serious & life-threatening infections, mainly those caused by gm +ve & gm -ve bacteria which are resistant to other antibiotics. Lower resp tract, GUT, gynaecological, skin & skin structure, intra-abdominal, bone & joint, CNS infection. Bacteremia & septicemia.

Dosage/Direction for Use

Adult & childn >12 yr 1 g 12 hrly. Severe infection: 2 g twice daily. Max: 12 g daily. Infant & childn 1 mth-12 yr (<50 kg) 50-180 mg/kg IM/IV daily in 4-6 divided doses. Neonate & premature infant 1-4 wk 50 mg/kg daily in divided doses every 8 hr, <1 wk 50 mg/kg IV 12 hrly.

Contraindications

Hypersensitivity to cephalosporins.

Special Precautions

Hypersensitivity to penicillins. Severe renal dysfunction. History of GI disease particularly colitis. Pregnancy & lactation.

Adverse Reactions

Hypersensitivity reactions, GI disturbances, superinfection, pain at inj site, phlebitis, transient leucopenia, eosinophilia, neutropenia.

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Drug Interactions

Aminoglycosides, potent diuretics & probenecid.

MIMS Class

Cephalosporins

ATC Classification

J01DD01 - cefotaxime ; Belongs to the class of third-generation cephalosporins. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Lapixime powd for inj 1 g

Packing/Price

1's (Rp82,000/vial)

Lapixime

cefotaxime

Manufacturer:

Lapi