Lapirom Dosage & Drug Information

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Concise Prescribing Info

Contents

Cefpirome

Indications/Uses

Lower resp tract infections (bronchopneumonia & lobar pneumonia), complicated upper & lower UTI (pyelonephritis), cellulitis, skin abscess, wound infections, infections in neutropenic & immunocompromised patients.

Dosage/Direction for Use

Complicated upper & lower UTI, skin & soft tissue infections, lower resp tract infections 1 g 12 hrly. Max: 2 g/day. Bacteremia/septicemia, severe infections or infections in patient w/ neutropenia 2 g 12 hrly. Max: 4 g/day.

Contraindications

History of hypersensitivity to β-lactams. Sensitivity to penicillin.

Special Precautions

Hypersensitivity to penicillin. May cause pseudomembranous colitis & cross-sensitivity w/ penicillin. Monitor blood count in prolonged treatment (>10 days). Renal impairment. Pregnancy & lactation.

Adverse Reactions

Hypersensitivity reactions, GI effects, interstitial nephritis, increased liver enzyme, haematological changes, thrombophlebitis, pain at inj site, convulsion, reversible encephalopathy, superinfections.

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Drug Interactions

Aminoglycosides, diuretics, probenecid; false +ve in Coombs' test; may cause creatinine-like reactions in creatinine test using picrate method.

MIMS Class

Cephalosporins

ATC Classification

J01DE02 - cefpirome ; Belongs to the class of fourth generation cephalosporins. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Lapirom powd for inj 1 g

Packing/Price

1's

Lapirom

cefpirome

Manufacturer:

Lapi