Hepagusan Adverse Reactions

Inj: Anticoagulant therapy and prophylaxis of thrombo­embolism: Heparin may occasionally lead in transient and re­versible hair loss as well as to thrombocytopenia. Both symptoms disappear however upon cessation of therapy.
After long-term therapy over more than 1 year signs of osteoporosis may be observed.
Local or generalized allergic reactions following Heparin medication occur only very seldom.
Additionally in case of anticoagulant therapy: Sporadic side-eftects like headache, nausea, itching and rise of body temperature have been reported. Normally this is no compelling reason to discontinue Heparin therapy.
Prophylaxis of thromboembolism: The occurrence of haematoma formation is very sel­dom as long as the recommended injection technique is adhered to.
Bleeding in the wound can increase especially if thrombin and partial thromboplastin time is long lasting. In such cases the Heparin dose is to be decreased and the time interval of 8 hours prolonged. If required, the Heparin effect can be rapidly neutralized by giving Protamine Hydrochloride or Sulphate.
The Benzyl alcohol added as preservative to the Heparin solution may give rise to allergic skin reactions in isolated cases.
Local irritation: Allergic manifestation caused by Heparin: Haemorrhage manifestation.
Increased transaminase enzyme.
Hypereosinophilia.