Glutazon Dosage & Drug Information

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Concise Prescribing Info

Contents

Pioglitazone

Indications/Uses

Adjunct to diet & exercise to improve glucose control in patients w/ type 2 DM. Monotherapy & combination therapy w/ sulfonylurea or metformin if diet & exercise along w/ one of these medications do not provide adequate blood glucose control. Combination therapy w/ metformin & sulfonylurea if dual combination therapy does not provide adequate glycemic control (especially in overwt patients).

Dosage/Direction for Use

Monotherapy: Initially 15 or 30 mg once daily. Gradually increase the dose to 45 mg once daily. Combination therapy: Initially 15 or 30 mg once daily. Metformin & sulfonylurea doses may be continued after initiating therapy. If hypoglycemia occurs, reduce the dose of sulfonylurea.

Administration

May be taken with or without food.

Contraindications

Hypersensitivity. Patients w/ heart failure or a history of heart failure (NYHA stage I-IV), kidney damage, diabetic ketoacidosis, bladder cancer or history of bladder cancer. Patients using insulin.

Special Precautions

Discontinue use if ALT levels increase 3x ULN. Fluid retention & heart failure. Monitor liver enzymes. Strictly control calorie intake. Risk of hypoglycemia in combination w/ sulfonylurea. Not recommended in patients <18 yr.

Adverse Reactions

Visual disturbances, resp tract infection & sinusitis, hypoesthesia, insomnia.

View ADR Reporting Link

Drug Interactions

Increased risk of edema w/ NSAIDs. Concomitant use w/ gemfibrozil, rifampicin.

MIMS Class

Antidiabetic Agents

ATC Classification

A10BG03 - pioglitazone ; Belongs to the class of thiazolidinediones. Used in the treatment of diabetes.

Regulatory Classification

Presentation/Packing

Form

Glutazon tab 30 mg

Packing/Price

3 × 10's

Glutazon

pioglitazone

Manufacturer:

Konimex