Farmabes Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Diltiazem HCl

Indications/Uses

Tab: Angina pectoris. Inj: Atrial fibrillation/flutter, paroxysmal supraventricular tachycardia.

Dosage/Direction for Use

Tab Adult 30 mg 4 times daily. May be increased gradually to 360 mg daily in 3-4 divided doses. Inj Direct IV bolus: Adult Supraventricular tachyarrhythmia 10 mg slow IV over 3 min. Management of abnormal BP increase during operation 10 mg slow IV over 1 min, followed by IV drip infusion at a rate of 5-15 mcg/min/kg. Hypertensive emergency IV drip infusion at a rate of 5-15 mcg/min/kg. After BP is decreased to the target level, the rate of drip infusion is adjusted to such level as indication by BP monitoring.

Administration

Should be taken on an empty stomach.

Contraindications

Sick sinus syndrome, 2nd- & 3rd-degree AV block, hypotension.

Special Precautions

1st-degree AV block. CHF. Hepatic or renal impairment. Pregnancy & lactation. Childn.

Adverse Reactions

Headache; hypotension. Tab: Ankle edema; flushing; GI discomfort. Weakness, shoulder & elbow pain, akathisia. Bradycardia. Rarely, sinus arrest; gynecomastia. Inj: Arrhythmia, itching, burning pruritus, sweating, constipation, nausea, vomiting, dizziness, paresthesia, dry mouth, dyspnea, edema,

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Drug Interactions

Enhances antihypertensive effect of β-blockers. Increases plasma level of digoxin. Plasma conc increased by cimetidine.

MIMS Class

Calcium Antagonists

ATC Classification

C08DB01 - diltiazem ; Belongs to the class of benzothiazepine derivative selective calcium-channel blockers with direct cardiac effects. Used in the treatment of cardiovascular diseases.

Regulatory Classification

Presentation/Packing

Form

Farmabes inj 5 mg/mL

Packing/Price

(vial) 5 mL x 1's (Rp90,000/vial)

Form

Farmabes tab 30 mg

Packing/Price

100's (Rp45,000/pak)

Farmabes

diltiazem

Manufacturer:

Fahrenheit