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Avoid use in patients with pre existing renal dysfunction.
Discontinue use of HES product at the first sign of renal injury.
Continue to monitor renal function in hospitalized patients for at least 90 days as use of RRT has been reported up to 90 days after administrations of HES products.
In severe dehydration a crystalloid solution should be given first.
Monitor liver function in patients receiving HES products.
Monitor kidney function, fluid balance and serum electrolytes.
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