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Diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus B vaccine - Intramuscular


Patient Medicine Information
Why do I need this medicine?
Diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus influenzae type B vaccine helps protect infants and children against diphtheria, tetanus, pertussis, polio and Haemophilus influenzae type B infections.

Diphtheria is a serious bacterial infection that mainly affects the airways, causing swelling and leading to serious breathing problems. It may also affect the skin, causing sores and skin covered by grey tissue.

Tetanus is a serious bacterial infection that causes painful muscle spasms and stiffness, particularly of the neck and jaw. The bacteria can enter the body through breaks in the skin, usually cuts, scratches, or wounds.

Pertussis or whooping cough is a very contagious bacterial infection that affects the airways causing severe coughing (often characterised by a "whooping" sound).

Poliomyelitis or polio is an infectious viral disease characterised by muscle paralysis.

Haemophilus influenzae type B is a type of bacteria that can lead to various serious illnesses such as blood infection, meningitis (infection of the lining covering the brain and spinal cord), pneumonia (an infection that causes inflammation of one or both lungs), and epiglottitis (infection in a part of the windpipe).

This medicine helps the body make antibodies (substances in the body that help fight infection) to protect infants and children against these infections.
How do I use this medicine?
Diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus influenzae type B vaccine is to be given intramuscularly (into the muscle), usually into the muscles of the thigh or upper arm.

A doctor or nurse will administer the injection to your child.

The total number of injections that your child will receive will be decided by the doctor.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with the doctor so that your child does not miss any doses.

If your child misses an appointment or an injection, alert the doctor or nurse.
When should I not use this medicine?
Do not use Diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus influenzae type B vaccine if your child ever had an allergic reaction (e.g. rashes, breathlessness, swollen eyes) to this medicine or any of its ingredients.

Alert the doctor if your child has the following conditions:
  • history of brain disease from an unknown cause occurring within 7 days of previous vaccination with a pertussis-containing vaccine
  • uncontrolled brain or nervous system illness
as Diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus influenzae type B vaccine may not be suitable for your child.
What should I take note of while using this medicine?
Inform the doctor if your child has the following conditions:
  • history of fever ≥40°C of unknown cause, collapse, and continuous inconsolable crying that occurred within 48 hours of immunisation against pertussis infection
  • history of fits or seizures that occurred within 3 days of immunisation against pertussis infection
  • history of Guillain-Barre syndrome (a rare disorder in which your body's immune system attacks your nerves) that occurred within 6 weeks of immunisation against tetanus infection
  • bleeding problems
  • weak immune system
If your child is going to have any laboratory tests, inform the doctor that your child was recently immunised with Diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus influenzae type B vaccine.
What side effects could I experience?
Diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus influenzae type B vaccine may cause any of the following side effects: sleepiness, vomiting, diarrhoea, loss of appetite, fever, irritability, and pain, swelling or redness at the injection site.

Some side effects may need immediate medical help. Alert the doctor quickly if your child experiences any of the following:
  • rashes, breathlessness, swelling of the face, eyes or mouth
  • temporary loss of consciousness or fainting
  • inconsolable crying, very high fever, fits or seizures
Inform the doctor if any of these side effects do not go away or are severe, or if your child experiences other side effects.
Can I use this with other medicines?
Always notify the doctor and pharmacist if your child is taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
How should I store this medicine?
Store in the refrigerator, between 2-8°C.

Do not freeze Diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus influenzae type B vaccine otherwise, it will no longer be effective and should not be used.

Protect from light.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on Diphtheria, tetanus, pertussis, poliomyelitis and Haemophilus B vaccine - Intramuscular and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2025 MIMS. All rights reserved. Powered by MIMS.com
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